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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Helminth Infections / Helminthiasis

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Following helminth infection, the intestinal epithelial cells secrete “alarmin” cytokines, such as IL-25 and IL-33, to initiate the type 2 immune responses for helminth expulsion and tolerance.
Zhao et al. 2022 Immunity 55: 623-638.e5

The schistosome oligosaccharide Lacto-N-neotetraose expands Gr1(+) cells that secrete [Anti-inflammatory cytokines](brain://Es…

Fermentable Dietary Fiber Promotes Helminth Infection and Exacerbates Host Inﬂammatory Responses
Myhill et al. 2020 J Immunol 204: 3042
Soil-transmitted helminth infections in humans: Clinical management and public health control
Jourdan et al. 2018 The Lancet 391: 252-265
The amalgam of naive CD4+ T cell transcriptional states is reconfigured by helminth infection to dampen the amplitude of the immune response
Even et al. 2024 Immunity 57(8): 1893-1907
The Role of the Intestinal Epithelium in the "Weep and Sweep" Response during Gastro-Intestinal Helminth Infections
Baska & Norbury 2022 Animals (Basel) 12: 175
Review
The Schistosome Oligosaccharide Lacto-N -neotetraose Expands Gr1 + Cells That Secrete Anti-inflammatory Cytokines and Inhibit Proliferation of Naive CD4 + Cells: A Potential Mechanism for Immune Polarization in Helminth Infections
Terrazas et al., 2001 J. lmmunol. 167: 5294

2/27/2026