meRfi®-GM
Macroautophagy / Autophagy
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Contents
Phagocytosis of own cellular components is macroautophagy / autophagy. Parts of the cell are degraded in the lysosome
Macroautophagy does not only affect proteins but can attack entire organelles and non-proteinaceous macromolecules
Autophagy is a crucial process involved in quality control, metabolism, and innate immunity. It plays a significant role in maintaining cellular health across various cell typ…
References (Sources)
- Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors
- Hallmarks of aging: An expanding universe
- Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- PAMPs and DAMPs: signal 0s that spur autophagy and immunityReview
- Self-eating and self-killing: crosstalk between autophagy and apoptosis
- The Cvt pathway as a model for selective autophagy.
- Unconventional secretion by autophagosome exocytosis