meRfi®-GM
Innate Immune System / Innate immunity
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Contents
Innate immunity, once overlooked, is now recognized as crucial in immunology. It serves as the first line of defense against infection in vertebrates and is the sole defense mechanism in invertebrates and plants. Innate immunity also plays a vital role in maintaining homeostasis, shaping the microbiota, and is involved in various diseases. The study of innate immunity has expanded our understanding of the immune system beyond vertebrates to include all metazoans, plants, and even prokaryotes.
The innate immune system in eukaryotes and bacteria (gut microbiota) is similar. It is part of the broad arse…
References (Sources)
- Bacterial origins of human cell-autonomous innate immune mechanisms
- Infection infidelities drive innate immunity
- Innate Antiviral Immunity in the SkinReview
- Innate immunity: the bacterial connection
- Phage defense origin of animal immunity
- Stimulus-specific responses in innate immunity: Multilayered regulatory circuits
- The conceptual foundations of innate immunity: Taking stock 30 years later