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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

Gut bacteria

Human gut bacteria convert the secondary bile acid lithocholic acid with 3alfa-Hydroxysteroid Dehydrogenase into 3-Oxol-lithocholic acid (3-oxoLCA) as well as the abundant gut metabolite Isolithocholic acid (isoLCA))
Paik et al. 2022 Nature 603: 907

Gut bacteria play a crucial role in maintaining the health of the gastrointestinal tract. They:

These activities help normalize the functioning of the gastrointestinal tract. However, gut [dy…

Diet Drives Convergence in Gut Microbiome Functions Across Mammalian Phylogeny and Within Humans
Muegge et al. 2011 Science 332: 970-974
Experimental evolution makes microbes more cooperative with their local host genotype
Batstone et al. 2020 Science 370: 476-478
Gut microbiota functions: metabolism of nutrients and other food components
Rowland et al. 2018 Eur. J. Nutr. 57: 1-24
Review
Gut microbiota: Role in pathogen colonization, immune responses, and inﬂammatory disease
Pickard et al. 2017 Immunol Rev. 279(1): 70-89
Host-microbiota interactions in inﬂammatory bowel disease
Caruso et al. 2020 Nat Rev Immunol 20: 411-426
Review
Human gut bacteria produce Τh17-modulating bile acid metabolites
Paik et al. 2022 Nature 603: 907
Small molecules from the human microbiota
Donia & Fischbach 2015 Science 349: 1254766