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A disruption of the gut microbiome favors the colonization, proliferation, and production of Clostridioides (Clostridium) difficile toxins, which damage the intestinal epithelial layer.
Clostridioides difficile infection (CDI), particularly when recurrent, is linked to a reduction in microbial diversity and a decrease in microbe-derived secondary bile acids. These acids play a crucial role in inhibiting the germination and growth of [Clostridioides (Clostridium) difficile](brain://S1Y4QnhYKEC6XibNxuhXIQ…