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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Foxp3 / FOXP3 / Scurfin

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Aliases: AIID, DIETER, IPEX, JM2, PIDX, XPID, forkhead box P3

Foxp3 / FOXP3 / Scurfin is acetylated for best binding to DNA
Greene & Waldmann 2010 Current Opinion in lmmunology 22: 549-551

Abnormalities of Foxp3 / FOXP3 / Scurfin lead to progressive autoimmune processes
Greene & Waldmann 2010 Current Opinion in lmmunology 22: 549-551

T cells express Foxp3 when TCR is stimulated by self-peptide / MHC complex
Ohkura et al., 2010

Expression of FOXP3 at low levels induces a limited T R…

An essential role for Scurﬁn in CD4 + CD25 + T regulatory cells
Khattri et al. 2003 Nat. Immunol 4: 337-342
CD8 + suppressor T cells resurrected
Kapp & Bucy, 2008
Review
Current trends with FOXP3+ regulatory T cell immunotherapy to contest autoimmunity and inflammation
Trinath & Bayry 2019
FOXP3 + regulatory T cells in the human immune system
Sakaguchi et al. 2010 Nature 10: 490
Review
Foxp3 Occupancy and Regulation of Key Target Genes During T-Cell Stimulation
Marson et al. 2007 Nature 445(7130): 931-5
Regulation of the immune response
Greene & Waldmann 2010 Current Opinion in lmmunology 22: 549-551
Regulatory T cells: roles of T cell receptor for their development and function
Ohkura et al., 2010
Review

12/16/2025