meRfi®-GM
Foxp3 / FOXP3 / Scurfin
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Contents
Aliases: AIID, DIETER, IPEX, JM2, PIDX, XPID, forkhead box P3
Foxp3 / FOXP3 / Scurfin is acetylated for best binding to DNA
Abnormalities of Foxp3 / FOXP3 / Scurfin lead to progressive autoimmune processes
T cells express Foxp3 when TCR is stimulated by self-peptide / MHC complex
Expression of FOXP3 at low levels induces a limited T R…
References (Sources)
- An essential role for Scurfin in CD4 + CD25 + T regulatory cells
- CD8 + suppressor T cells resurrectedReview
- Current trends with FOXP3+ regulatory T cell immunotherapy to contest autoimmunity and inflammation
- FOXP3 + regulatory T cells in the human immune system
- Foxp3 Occupancy and Regulation of Key Target Genes During T-Cell Stimulation
- Regulation of the immune response
- Regulatory T cells: roles of T cell receptor for their development and functionReview