bolismCholesterol) 22:T5f7,

In the classical pathway, cholesterol 7-alfa-hydroxylase (CYP7A1), as the ﬁrst enzyme, converts rate-limiting cholesterol to 7alfa-hydroxycholesterol
Way et al. 2022 Cells 11: 1374

The enzyme (encoded by CYP7A1) initiates Bile Acids / Bile Salts synthesis via the classical route
Schubert et al. 2017 Immunological Reviews 279: 23-35

FGF19 interaction with FGFR4 induces transcriptional repression of cyp7a1 Gene Non-m
Schubert et al. 2017 Immunological Reviews 279: 23-35

see also:
Catabolism & Cholesterol

25:T505,In the classical pathway, cholesterol 7-alfa-hydroxylase (CYP7A1) [?id=50fb5039-8856-419d-ac05-b7402e884c93&linkText=cholesterol+7-alfa-hydroxylase+%28CYP7A1%29], as the ﬁrst enzyme, converts rate-limiting cholesterol [?id=6ca83ea9-6121-4e00-8522-9fc0340d6497&linkText=cholesterol] to 7alfa-hydroxycholesterol [?id=6b9be43c-9891-40e8-b2f1-294f7596c732&linkText=7alfa-hydroxycholesterol] Way et al. 2022 Cells 11: 1374 [?id=e62c9960-3c80-40da-9c45-9a1459e30653&linkText=%3Cspan+class%3

Cholesterol 7 alfa-hydroxylase (CYP7A1)

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