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Cholesterol 7 alfa-hydroxylase (CYP7A1)

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In the classical pathway, cholesterol 7-alfa-hydroxylase (CYP7A1), as the first enzyme, converts rate-limiting cholesterol to 7alfa-hydroxycholesterol
Way et al. 2022 Cells 11: 1374

The enzyme (encoded by CYP7A1) initiates Bile Acids / Bile Salts synthesis via the classical route
Schubert et al. 2017 Immunological Reviews 279: 23-35

FGF19 interaction with [FGFR4](brain://8x36s42bYU6wl24hLGjEfw/Fibrobla…