meRfi®-GM
Non-Nutritive Sweeteners (NNS) / Sugar Substitutes
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Non-nutritive sweeteners (NNS) are commonly integrated into human diet and presumed to be inert
Animal studies suggest that they may impact the microbiome and downstream glycemic responses.
Each administered NNS distinctly altered stool and oral microbiome and plasma metabolome, whereas saccharin and sucralose significantly impaired glycemic responses.
Importantly, gnotobiotic mice conventionalized with microbiomes from multiple top and bottom re…