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ZDHHC5

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The palmitoyl acyltransferase ZDHHC5 is a member of the ZDHHC (zinc finger DHHC-type containing) family of proteins, which are responsible for catalyzing S-palmitoylation, a post-translational modification that involves the addition of a palmitate group to proteins
Main et al. 2022 Front Physiol 13: 1023237

This enzyme is primarily localized at the cell surface and is known to form a complex with GOLGA7, enhancing its palmitoylation activity
Ko et al. 2019 Cell Chem Biol 26(12): 1716-1724

The palmitoyl acyltransferase ZDHHC5 regulates NLRC1 / NOD1 (NOD-like receptor family CARD Domain-Containing Protein 1) and [NLRC2 / NOD2 (NOD-like receptor family CARD Domain-Conta…