meRfi®-GM
Palmitoylation
Welcome to meRfi-GM!
meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.
Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.
Start your free trial and transform your understanding of the gut microbiota today!
Contents
Protein palmitoylation is a type of reversible post-translational modification in which a 16-carbon fatty-acid palmitate attaches to the cysteine residue of a target protein, and which has been shown to regulate cancer development and the innate immune system
Protein palmitoylation has been shown to play a crucial role in immune regulation. For example, palmitoylation of NOD-like receptor 1 (NOD1) and NOD2 by ZDHHC5 is essential for its membrane localization and bacterial recognition
Palmitoylation of the [stim…
References (Sources)
- Activation of STING requires palmitoylation at the Golgi
- Palmitoylation of NLRP3 Modulates Inflammasome Activation and Inflammatory Bowel Disease Development
- Palmitoylation of NOD1 and NOD2 is required for bacterial sensing
- Signalling functions of protein palmitoylation
- Signalling functions of protein palmitoylation