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NOD-like receptors (NLRs) & ZDHHC5

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In the case of mutations on Nucleotide-binding oligomerization domains (NODs), the S-palmitoylation and the stimulation by the bacterial peptidoglycans cannot happen; severe immunologic and inflammatory diseases such as Crohn's disease (CD) or Blau syndrome result
Lu et al. 2019 Science 366: 460-467