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Fecal calprotectin (FCal)
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Fecal calprotectin is a marker for Inflammatory Bowel Disease (IBD) severity.
Inflammation assessed by fecal calprotectin ≤ or > 100 μg/mg (FCP)
Fecal calprotectin (FCal) is a well-known fecal biomarker that is used to help both distinguish Inflammatory Bowel Disease (IBD) from Irritable Bowel Syndrome (IBS) and to determine whether an IBD patient has an exacerbation. During intestinal inflammation, FCal is secreted by neutrophils in the gut, leading to an increase in FCal levels in…
References (Sources)
- A combination of fecal calprotectin and human beta-defensin 2 facilitates diagnosis and monitoring of inflammatory bowel disease
- Discovery of disease-adapted bacterial lineages in inflammatory bowel diseases
- Faecal calprotectin for screening of patients with suspected inflammatory bowel disease: diagnostic meta-analysis
- Fecal Calprotectin Is Highly Effective to Detect Endoscopic Ulcerations in Crohn's Disease Regardless of Disease Location
- Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome
- Impact of disease location on fecal calprotectin levels in Crohn’s disease
- Meta-analysis: fecal calprotectin for assessment of inflammatory bowel disease activityMeta-Analysis