Bile salts / Bile acids & Cancer

Conjugated bile acids were more potent than unconjugated cholic acid in reducing pancreatic cancer cell survival
Shrader et al. 2021

Recent evidence also suggests that Bile salts / Bile acids promote anti-tumor immune response through activation and recruitment of tumoricidal immune cells such as natural killer T cells
Sipe et al. 2020 Immunol Rev 295: 220-239

At high concentrations, Bile salts / Bile acids play a pro-inflammatory or even carcinogenic role in vitro and in vivo
Kajiura et al. 1998 Digestion 59: 69–72
Zhao et al. 2016 Front. Immunol. 7: 536
Pols et al. 2017 Plos One 12: e0176715

see also:
Oncomicrobes