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Toll-Like Receptor 3 (TLR-3) is endosomal localized
Toll-Like Receptor 3 (TLR-3) is unique among Toll-Like Receptors (TLRs) as it does not activate via the MyD88 / NFKB / MAPK Signal transduction Pathway. Instead, it activates NFKB and Interferon (IFN) Regulatory Factor 3 (IRF3) through the TRIF-Dependent Pathway
Toll-Like Receptor 3 (TLR-3) engagement increases production of Interferons Type I (IFN Type I), [Interferon type III (IFN…