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TRIF-Dependent Pathway
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TRIF-Dependent Pathway refers to a MyD88-independent signaling cascade initiated by certain Toll-like receptors (TLRs) - notably TLR3 and TLR4 - through the adaptor protein TRIF (TIR-domain-containing adapter-inducing interferon-beta). The TIR domain-containing adapter molecule 2 (TICAM2), [TIR domain containing adaptor molecule 1 (TICAM1)](brain://Yke6tVkLO1Wp2z7i6McE2w/TirDomainContainingAdaptorMolec…