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CD284 (Toll-Like Receptor 4 (TLR-4))
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Contents
It cooperates with LY96 (also referred as MD-2) and CD14 to mediate in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria.
Toll-Like Receptor 4 (TLR-4) is localized on cell membranes of CD11c + Conventional dendritic cell (cDC) / myeloid dendritic cell (mDC)), Monocytes, Basophils, [Mastocytes / Mast ce…
References (Sources)
- .01 Pattern recognition receptors: immune targets to enhance cancer immunotherapy
- Activation of TLR4 signaling promotes gastric cancer progression by inducing mitochondrial ROS production
- CD14 controls the LPS-induced endocytosis of Toll-like receptor 4
- CD74 and macrophage migration inhibitory factor as therapeutic targets in gastric cancer
- Recognition and signaling by Toll-like receptors
- Targeting TLR4-dependent inflammation in post-hemorrhagic brain injury
- Toll‑like receptor 4 plays a tumor‑suppressive role in cutaneous squamous cell carcinoma