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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Candidiasis

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Individuals with immunosuppression due to hematologic malignancies, organ transplantation, AIDS, or prolonged intensive care hospitalization are highly susceptible to invasive candidiasis
Gander-Bui et al. 2023 Immunity 56: 1743-1760

Invasive candidiasis has high mortality rates in immunocompromised patients, causing severe health problems.
Nu et al. 2022 J Immunol 208: 660-671

References (Sources)

CX3CR1-dependent renal macrophage survival promotes Candida control and host survival
Lionakis et al. 2013 J. Clin. Invest. 123: 5035-5051
IL-33 Coordinates Innate Defense to Systemic Candida albicans Infection by Regulating IL-23 and IL-10 in an Opposite Way
Nu et al. 2022 J Immunol 208: 660-671
Inflammatory Ly6C high monocytes protect against Candidiasis through IL-15-driven NK cell/neutrophil activation
Domínguez-Andrés et al. 2017 Immunity 46: 1059-1072
Inflammatory monocytes mediate early and organ-specific innate defense during systemic candidiasis
Ngo et al. 2014 J. Infect. Dis. 209: 109-119
Invasive candidiasis
Kullberg & Arendrup 2015 N. Engl. J. Med. 373: 1445–1456
Targeted removal of macrophage-secreted interleukin-1 receptor antagonist protects against lethal Candida albicans sepsis
Gander-Bui et al. 2023 Immunity 56: 1743-1760
Type I interferons promote fatal immunopathology by regulating inflammatory monocytes and neutrophils during Candida infections
Majer et al. 2012 PLoS Pathog. 8: e1002811

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Candidiasis

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