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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

CD284 (Toll-Like Receptor 4 (TLR-4)) & Morbus Parkinson / Parkinson's disease (PD)

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CD284 (Toll-Like Receptor 4 (TLR-4))-mediated inflammation plays an important role in intestinal and/or brain inflammation, which may be one of the key factors leading to neurodegeneration in Morbus Parkinson / Parkinson's disease (PD).
Perez-Pardo et al. 2019 Gut 68: 829-843

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Role of TLR4 in the gut-brain axis in Parkinson’s disease: a translational study from men to mice
Perez-Pardo et al. 2019 Gut 68: 829-843
TLR2 and TLR4 in Parkinson’s disease pathogenesis: the environment takes a toll on the gut
Gorecki et al. 2021 Translational Neurodegeneration 10: 47
Review

5/29/2026