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Protein post-translational modifications (PTMs) act as molecular switches. They modulate cell signaling. This occurs in response to developmental or external signals. Recent studies show that some bacteria use unique PTMs. These are called orthogonal post-translational modifications (oPTMs). They assist in creating niches that enable bacterial replication.
Post-translational modifications (PTMs) immensely expand the diversity of the proteome.
Substantial post-translational modifications of proteins are, in particular, N-glycosylation and [O-glycosylation](brain:…