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Various cancer tissues have been analyzed to express the T, Tn (GalNAc-O-Ser/Thr), and Sialyl-Tn (STn) / Neu5Acα2-6GalNAc-O-Ser/Thr antigens
Galectins are mostly expressed by tumor cells and support tumor-cell survival
Tumor-cell Derived Glycans Bind to Glycan-binding Receptors - Lectins
Malignant transformation of cells is associated with aberrant [g…