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Cancer cells / Tumor cells

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Contents

Various cancer tissues have been analyzed to express the T, Tn (GalNAc-O-Ser/Thr), and Sialyl-Tn (STn) / Neu5Acα2-6GalNAc-O-Ser/Thr antigens
Cazet et al. 2010 Breast Cancer Res 12: 204
Fu et al. 2016 HLA 88: 275–86
Munkley, 2016

Galectins are mostly expressed by tumor cells and support tumor-cell survival
Häuselmann & Borsig 2014

Tumor-cell Derived Glycans Bind to Glycan-binding Receptors - Lectins
Häuselmann & Borsig 2014

Malignant transformation of cells is associated with aberrant [g…