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The epidemiology of Clostridioides (Clostridium) difficile has changed markedly over the decades, with high Clostridioides difficile infection (CDI) rates driven by clinical pressures exacerbated by the severe acute respiratory syndrome Covid-19 / SARS-CoV-2 pandemic, antibiotic resistance and selective pressures caused by antimicrobial use.
The Centers for Disease Control and Prevention (CDC) estimates that [Clostridioides difficile infection (C…