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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Clostridioides difficile infection (CDI)

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Contents

Clostridioides difficile (CDI) intestinal infections are among the most common nosocomial infections in high-income countries. It is the leading cause of healthcare-associated infectious enteric inflammations worldwide.
Li & Saavedra 2025 mBio 16: e03562-24

Clostridiodes difficile infection (CDI) is a life-threatening illness that has been labelled as an urgent threat by the Centers for Disease prevention (CDC). It is linked to a high rate of death and disease.
Chopra 2023 Expert Review of Anti-Infective Therapy 21(3): 243-253
Garey et al. 2023 JAMA Netw Open 6: e2253570

In Europe, approximately 198,526 cases are reporte…

References (Sources)

Clostridioides difficile infections - new treatments and future perspectives.
Normington et al. 2024 Curr Opin Gastroenterol 40(1): 7-13
Review
Clostridium difficile infection
Smits et al. 2016 Nat Rev Dis Primers 2: 16020
Clostridium difﬁcile-associated disease in Oregon: increasing incidence and hospital-level risk factors
Chandler et al. 2007 Infect Control Hosp Epidemiol 28: 116-122
Emergence of ﬂuoroquinolones as the predominant risk factor for Clostridium difﬁcile-associated diarrhea: a cohort study during an epidemic in Quebec
Pépin et al. 2005 Clin Infect Dis 41: 1254-1260
Management of Clostridioides difficile infection in adults and challenges in clinical practice: review and comparison of current IDSA/SHEA, ESCMID and ASID guidelines.
Bishop & Tiruvoipati 2022 J Antimicrob Chemother 78(1): 21-30
Recurrent Clostridioides difficile infection worsens anxiety-related patient-reported quality of life
Hengel et al. 2022 J Patient Rep Outcomes 6(1): 49
Update of Clostridium difﬁcile infection due to PCR ribotype 027 in Europe 2008
Kuijper et al. 2008 Euro Surveill 13(31)

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Links

Clostridioides difficile infection - Wikipedia
https://www.cdc.gov/cdiff/materials.html.
https://doi.org/10.1007/978-3-319-74932-7_13