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The brain and gut are connected. Enteroendocrine Cells (EEC) play a role similar to the gut's role with the brain. They manage GI tract functions. Vagal afferent fibers reach the GI tract wall. They contact the intestinal lining. EECs secrete products that act on these fibers. This activates the fibers.
The release of basal 5-HT can activate vagal afferent fibers, which induces intestinal motility. Additionally, through gut-brain axis signaling, it promotes […