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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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AvRa & Salmonella enterica enterica Typhimurium

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Salmonella typhi strains that maintain chronic infections secrete AvrA, which can activate epithelial beta-catenin signaling, and are associated with hepatobiliary cancers
Dutta et al. 2000 Am. J. Gastroenterol. 95: 784–787
Wistuba & Gazdar 2004 Nat. Rev. Cancer. 4: 695–706
Lazcano-Ponce et al. 2001 CA Cancer J. Clin. 51:349–364
Lu et al. 2012 Am. J. Physiol. Gastrointest. Liver Physiol. 303: G1113–G1125
Lu et al. 2014 Oncogenesis. 3: e105

Salmonella AvrA increases Akt/pho-beta-catenin in vivo
Lu et al. 2012 Am. J. Physiol. Gas…

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Consistent activation of the beta-catenin pathway by Salmonella type-three secretion effector protein AvrA in chronically infected intestine
Lu et al. 2012 Am. J. Physiol. Gastrointest. Liver Physiol. 303: G1113–G1125
Enteric bacterial protein AvrA promotes colonic tumorigenesis and activates colonic beta-catenin signaling pathway
Lu et al. 2014 Oncogenesis. 3: e105
Epidemiology and molecular pathology of gallbladder cancer
Lazcano-Ponce et al. 2001 CA Cancer J. Clin. 51:349–364
Gallbladder cancer: lessons from a rare tumour
Wistuba & Gazdar 2004 Nat. Rev. Cancer. 4: 695–706
Review
Typhoid carriers among patients with gallstones are at increased risk for carcinoma of the gallbladder
Dutta et al. 2000 Am. J. Gastroenterol. 95: 784–787

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AvRa & Salmonella enterica enterica Typhimurium

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