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The gastrointestinal tract is continuously subjected to various challenges, necessitating the regulation of immune responses in the intestine to prevent inflammation. Immune mechanisms, particularly Group 3 ILCs (ILC3), are essential in maintaining intestinal health. When Group 3 ILCs (ILC3) become dysregulated, it can lead to the development of numerous diseases. Future immunotherapeutic approaches may focus on targeting Group 3 ILCs (ILC3) to restore gastrointestinal tolerance and promote tissue health.
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