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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

Bacillus subtilis

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Bacillus subtilis is a probiotic bacterium. It is Gram-positive and found in fermented foods. Studies show Bacillus subtilis has anti-inflammatory effects. Its exopolysaccharide (EPS) is responsible for this.
Jones & Knight 2012 Infect Immun 80: 710-719
Jones et al. 2014 J Immunol 192: 4813-4820
Paynich et al. 2017 J Immunol 198: 2689-2698
Paik et al. 2018 Infect Immun 87: e00791-18
Swartzendruber et al. 2019 Allergy 74: 819-821
Paik et al. 2020 Infect Immun 88: e0…

References (Sources)

Bacillaene and sporulation protect Bacillus subtilis from predation by Myxococcus xanthus
Müller et al. 2014 Appl Environ Microbiol 80: 5603-5610
Bacillus subtilis exopolysaccharide prevents allergic eosinophilia
Swartzendruber et al. 2019 Allergy 74: 819-821
Bacillus subtilis-mediated protection from Citrobacter rodentium-associated enteric disease requires espH and functional flagella
Jones & Knight 2012 Infect Immun 80: 710-719
Biosynthesis of bacillomycin D by Bacillus subtilis
Besson & Michel 1992 FEBS Lett 398(1): 18-21
Exopolysaccharide from Bacillus subtilis induces anti-inflammatory M2 macrophages that prevent T cell-mediated disease
Paynich et al. 2017 J Immunol 198: 2689-2698
Suppression of Staphylococcus aureus superantigen-independent interferon gamma response by a probiotic polysaccharide
Paik et al. 2020 Infect Immun 88: e00661-19
The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis
Butcher et al. 2007 Proc Natl Acad Sci USA 104(5): 1506-9

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Bacillus subtilis

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