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Imiquimod, a TLR7 agonist, was explored as a vaccine adjuvant to assess its potential in inhibiting breast cancer growth. Although it is recognized for its antitumor properties, imiquimod did not provide a protective effect in this particular scenario. This synthetic compound is often utilized in a 5% cream formulation to effectively treat skin tumors. The antitumor effects of imiquimod are multifaceted, with a significant mechanism being its capacity to modulate immune responses through the activation of TLR7/8.
Among the immune cells impl…