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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Muropeptides

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Muropeptides are soluble fragments derived from the peptidoglycan (PGN) layer of bacterial cell walls
Boudreau et al. 2012 Biochemistry 51(14): 2974-90
Irazoki et al. 2019 Front Microbiol 10: 500
Orsini Delgado et al. 2024 Gut Microbes 16(1): 2418412

They consist of a glycan (sugar) backbone linked to short peptide stems, and their specific structures can vary depending on the bacterial species and the enzymes involved in Peptidoglycan (PGN) remodeling
Boudreau et al. 2012 Biochemistry 51(14): 2974-90
Irazoki et al. 2019 Front Microbiol 10: 500
Jõers et al. 2019 Sci Rep 9: 18043

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References (Sources)

Messenger functions of the bacterial cell wall-derived muropeptides
Boudreau et al. 2012 Biochemistry 51(14): 2974-90
Muropeptides and muropeptide transporters impact on host immune response
Orsini Delgado et al. 2024 Gut Microbes 16(1): 2418412
Review
Muropeptides Stimulate Growth Resumption from Stationary Phase in Escherichia coli
Jõers et al. 2019 Sci Rep 9: 18043
Peptidoglycan Muropeptides: Release, Perception, and Functions as Signaling Molecules
Irazoki et al. 2019 Front Microbiol 10: 500
Review

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Muropeptides

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