meRfi®-GM
The Digital Textbook on Gut Microbiota and Beyond
Probiotics (living agents) & Inflammatory Bowel Disease (IBD)
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Contents
Inflammatory bowel disease , a idiopathic conditions where alterations in the normal microflora have been implicated as responsible for initiation, is an area where the use of probiotics has been regarded as promising
Sullivan & Nord 2005
Mode of action (MoA)
In inflammatory bowel diseases (IBD), the therapeutic benefit and mucosal healing from specific probiotics may relate to the modulation of dendritic cells (DCs).
CD80 and CD86 were induced by most probiotic strains in ulcerative colitis (UC) patients whereas only [B. bifidum](brain://Q71V5kfa9kq4PuNYgKuTBw/BBifidumCrohnsDiseaseC…
References (Sources)
- Immunomodulation and Generation of Tolerogenic Dendritic Cells by Probiotic Bacteria in Patients with Inflammatory Bowel Disease
- Lactobacillus casei and bifidobacterium lactis supplementation reduces tissue damage of intestinal mucosa and liver after 2,4,6-trinitrobenzenesulfonic acid treatment in mice
- Lactocepin secreted by Lactobacillus exerts anti-inflammatory effects by selectively degrading proinflammatory chemokines
- Probiotic Mixture Protects Dextran Sulfate Sodium-Induced Colitis by Altering Tight Junction Protein Expressions and Increasing Tregs
- Probiotics in Intestinal Mucosal Healing: A New Therapy or an Old Friend?
- Role of prebiotics, probiotics, and synbiotics in management of inflammatory bowel disease: Current perspectives
- The effectiveness of probiotics in the treatment of inflammatory bowel disease (IBD)-A Critical Review