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Enterochromaffin Cells (EC) cells act as chemosensors on the intestinal epithelium. They translate environmental stimuli into the production of serotonin (5-HT)
Enterochromaffin Cells (EC) recognize Interleukin-33 (IL-33) and release Serotonin (5-HT). Interleukin-33 (IL-33)-mediated release of Serotonin (5-HT) activates enteric neurons and subsequently promotes intestinal motility. For example, the immediate peristaltic movement facilitates the expulsion of [Trichuris muris…