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Antibiotic tolerance
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Contents
Antibiotic tolerance allows temporary survival without growth in lethal antibiotic doses, characterized by slower killing rates without resistance. Both persistence and tolerance are linked to bacterial physiology and environment, with potential molecular determinants. These mechanisms, alongside genetic resistance, contribute to persistent infections.
References:
see also:
Antibiotics & Pathogenic Bacteria
[Antibiotic persistence…
References (Sources)
- Definitions and guidelines for research on antibiotic persistence
- Distinguishing between resistance, tolerance and persistence to antibiotic treatment
- HipBA–promoter structures reveal the basis of heritable multidrug tolerance
- Molecular Mechanisms Underlying Bacterial Persisters
- Persisters: a distinct physiological state of E. coli
- Ranking of persister genes in the same Escherichia coli genetic background demonstrates varying importance of individual persister genes in tolerance to different antibiotics
- Tolerance to antibiotics affects response