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Intestinal macrophages
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Contents
APCs are responsible for sensing the luminal antigens. Then, they are responsible for presenting the antigens to the T cells in the Peyer’s patches and mesenteric lymph nodes
In eubiosis , intestinal macrophages are more effective at Clearing bacteria but have reduced Cytokine secretion relative to peripheral macrophages
Smythies et…
References (Sources)
- Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity
- Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses
- The puzzle of intestinal lamina propria dendritic cells and macrophages
- The Role of Fecal Microbiota Transplantation in the Treatment of Acute Graft-versus-Host Disease