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Intestinal mucosal macrophages
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Contents
APCs are responsible for sensing the luminal antigens. Then, they are responsible for presenting the antigens to the T cells in the Peyer’s patches and mesenteric lymph nodes
The tissue microenvironment is pivotal in the differentiation and activation of intestinal macrophages.
Intestinal mucosal macrophages play a crucial role in the body's…
References (Sources)
- Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice
- Dynamics of Colon Monocyte and Macrophage Activation During Colitis
- Origin, differentiation, and function of intestinal macrophages
- The puzzle of intestinal lamina propria dendritic cells and macrophages
- The Role of Fecal Microbiota Transplantation in the Treatment of Acute Graft-versus-Host Disease
- The short chain fatty acid butyrate imprints an antimicrobial program in macrophages
- Tissue-specific differentiation of colonic macrophages requires TGFb receptor-mediated signaling