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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Cancer / Tumors & Galectin-3 (Gal-3)

Galectin-3 appears to be increased in expression during increasing malignancy; this applies to Colorectal Cancer (CRC), Prostate cancer, Papillary thyroid cancer, and Breast Cancer / Mammacarcinoma, however, scarce data are available in gastric cancer.
Miyazaki et al. 2002 Oncol Rep 9: 1307-12
Lin et al., 2009

Phosphorylation of Galectin-3 is crucial for its anti-apoptotic activity
Liu & Rabinovich, 2005

Expression of galectin-3 is altered in cancer.
Califice et al., 2004

Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and thera- peutic procedures
Lahm et al., 2001 J Cancer Res Clin Oncol 127:375-86.
Galectin-3 and cancer (Review)
Califice et al., 2004
Galectin-3 Targeted Therapy with a Small Molecule Inhibitor Activates Apoptosis and Enhances Both Chemosensitivity and Radiosensitivity in Papillary Thyroid Cancer
Lin et al., 2009
Galectins as modulators of tumour progression
Liu & Rabinovich, 2005
Review
Increased expression of galectin-3 in primary gastric cancer and the metastatic lymph node
Miyazaki et al. 2002 Oncol Rep 9: 1307-12
Inhibition and Detection of Galectins
Pieters, 2006
Lactose-binding lectin expression in human colorectal carcinomas. Relation to tumor progression
Lotan et al. 1991 Carbohydr Res 213: 47-57

5/29/2026