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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

K cell

Named for Vesicles that differentiate from L cells. The identifying hormone (historically) is

K cells and their subtypes are located in the proximal small intestine, have the luminal receptors G-Protein Coupled Receptor 119 (GPR119), G-Protein Coupled Receptor 120 (GPR120), G-Protein Coupled Receptor 40 (GPR40), and release Gastric inhibitory polypeptide (GIP). They activate the insulin release
Furness et al. 2013a Nature Reviews Gastroenterology & Hepatology 10: 729-740

Examples of colocalization of hormones and/or their gene transcripts (most of recent data is from mouse):

Habib et al. 2012 Endocrinology 153: 3054-3065
Fothergill & Furness 2018 Histochem Cell Biol 150(6): 693-702

Diversity of enteroendocrine cells investigated at cellular and subcellular levels: the need for a new classification scheme.
Fothergill & Furness 2018 Histochem Cell Biol 150(6): 693-702
Review
Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry
Habib et al. 2012 Endocrinology 153: 3054-3065
The gut as a sensory organ
Furness et al. 2013a Nature Reviews Gastroenterology & Hepatology 10: 729-740
Review

5/29/2026