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Diseases / Disorders & Gut microbiota

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The human microbiome plays a crucial role in our understanding of health and disease. Researchers have noticed systematic differences in the microbiome's composition when comparing healthy individuals to those suffering from conditions linked to microbiota, such as colorectal cancer (Bullman et al. 2017; Hale et al. 2018 Genome Med 10: 78; Burns et al. 2018 PLoS Genet 14: e1007376) and inflammatory bowel disease (Matsuoka & Kanai 2015 Semin Immunopathol 37: 47-55). These observations highlight the significance of understanding what causes variations in the microbiome.
Abdill et al. 2025 Cell 188: 1100-1118