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Diseases / Disorders & Gut microbiota

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The diverse and complex human microbiome can hinder identifying clear links between the gut microbiome and specific diseases, complicating the translation of preclinical findings into human studies. This often leads to inconsistent or suboptimal results, especially in noncommunicable chronic disorders (NCDs).
Porcari et al. 2025 Cell 188: 2836

The human microbiome plays a crucial role in our understanding of health and disease. Researchers have noticed systematic differences in the microbiome's composition when comparing healthy individuals to those suffering from conditions linked to microbiota, such as colorectal cancer (Bullman …