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The roles of Interleukin-12 (IL-12) and Interleukin-17 Family / Interleukin-17 (IL-17) in Inflammatory Bowel Disease (IBD) pathogenesis are not fully understood.
Interleukin-12 (IL-12) mRNA levels were upregulated in active Ulcerative colitis (UC) and Crohn's disease (CD) compared to controls (P < 0.02). In remission, IL-12 mRNA expression was similar to control samples.
Histological examination showed significant d…