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Interleukin-12 (IL-12) is a heterodimeric cytokine encoded by two separate genes, IL-12A (p35) and IL-12B (p40). The active heterodimer (referred to as 'p70'), and a homodimer of p40 are formed following protein synthesis.
Interleukin-12 (IL-12) is a pro-inflammatory cytokine and a crucial factor for Th1 polarization
Interleukin-12 (IL-12) is produced in: