meRfi®-GM
Chemosensory receptors / Chemoreceptor
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Contents
Chemosensory receptors include G-protein coupled receptors (GPCRs), Nuclear receptors (Transcription factors), and Aryl Hydrocarbon Receptor (AhR). Their ligands are secondary metabolites, e.g., from the gut microbiota (e.g., Short-chain fatty acids (SCFAs) such as butyrate and [indoles](brain://OuBaNhIAa0OlybpJJTOFcQ/ArylHydrocarbonReceptorAhRIndol…
References (Sources)
- Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
- Conditioning of the immune system by the microbiome
- Metabolite-Sensing G Protein–Coupled Receptors—Facilitators of Diet-Related Immune Regulation
- The microbial metabolites, short chain fatty acids, regulate colonic Treg cell homeostasis