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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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CD32 (FcγRIIA / FcγRIIB)

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CD32 plays a crucial role in the immune system by mediating antibody-dependent cell-mediated cytotoxicity (ADCC) and phagocytosis of opsonized pathogens or cells.
Anania et al. 2019 Front Immunol. 10: 464

CD32 (FcγRIIA and FcγRIIB) is expressed on various immune cells, including monocytes, macrophages, neutrophils, B cells, and microglia in the brain
Jovanova-Nesic et al. 2012 Curr Aging Sci. 5(3): 209-17
Zhu et al. 2016a Int J Med Sci. 13(2): 154-60
Melki et al. 2020 Blood 136(25): 2933-2945
Liao et al. 2023 Microbiol Spectr. 11(3): e0290322

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References (Sources)

Aluminum excytotoxicity and neuroautotoimmunity: the role of the brain expression of CD32+ (FcγRIIa), ICAM-1+ and CD3ξ in aging
Jovanova-Nesic et al. 2012 Curr Aging Sci. 5(3): 209-17
Review
CLEC18A Impairs Phagocytosis by Reducing FcγRIIA Expression and Arresting Autophagosome-Lysosome Fusion
Liao et al. 2023 Microbiol Spectr. 11(3): e0290322
FcγRIIA expression accelerates nephritis and increases platelet activation in systemic lupus erythematosus
Melki et al. 2020 Blood 136(25): 2933-2945
Functional Role of FcγRIIB in the Regulation of Mesenchymal Stem Cell Function
Zhu et al. 2016a Int J Med Sci. 13(2): 154-60
The Human FcγRII (CD32) Family of Leukocyte FcR in Health and Disease
Anania et al. 2019 Front Immunol. 10: 464
Review

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