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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Antibiotics & Clostridioides difficile infection (CDI)

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Clostridioides difficile infection (CDI) primarily occurs in patients undergoing antibiotic treatment or chemotherapy (CT), creating an optimal environment for the growth and intestinal colonization of Clostridioides (Clostridium) difficile
Li & Saavedra 2025 mBio 16: e03562-24

Antibiotics reduce the overall diversity of the gut microbiota (dysbiosis), leading to Clostridioides difficile infection (CDI) through…

Decreased diversity of the fecal microbiome in recurrent Clostridium difficile-associated diarrhea
Chang et al. 2008 J Infect Dis 197: 435-8
Microbiologic factors affecting Clostridium difficile recurrence
Chilton et al. 2018 Clin Microbiol Infect 24: 476–82
Review
Role of the Intestinal Microbiota in Resistance to Colonization by Clostridium difficile
Britton & Young 2014
Review
The Butyrate-Producing Bacterium Clostridium butyricum Suppresses Clostridioides difficile Infection via Neutrophil- and Antimicrobial Cytokine−Dependent but GPR43/109a-Independent Mechanisms
Hayashi et al. 2021a
The evolution of the use of faecal microbiota transplantation and emerging therapeutic indications
Allegretti et al. 2019 Lancet 394: 420-31
Review
The interplay between host immunity and Clostridioides difficile infection
Li & Saavedra 2025 mBio 16: e03562-24
Review

12/16/2025