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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Group 1 ILCs (ILC1) & Inflammatory Bowel Disease (IBD)

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Interferon Type II (IFN Type II) / Interferon Gamma (IFN-g)-producing CD127+ Group 1 ILCs (ILC1) accumulated in the inflamed ileum of Crohn's disease (CD) patients. The expansion was associated with disease severity
Bernink et al. 2013 Nat Immunol 14: 221-229
Li et al. 2016c Cell Immunol 304-305: 63-68

Fuchs et al. (2013) identified the expansion of CD103+ ILC1s which were also CD56+ in the intraepithelial compartment of Crohn's disease (CD) patients’ gut.
Fuchs et al. 2013 Immunity 38: 769-781

see also:
[Inflammatory Bowel Disease (IBD) & Innate Lymphoid Cells (ILCs)](brain://e9Aosj…

References (Sources)

Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues
Bernink et al. 2013 Nat Immunol 14: 221-229
Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-gamma-producing cells
Fuchs et al. 2013 Immunity 38: 769-781
The differential frequency of Lineage(-)CRTH2(-)CD45(+)NKp44(-)CD117(-)CD127(+)ILC subset in the inflamed terminal ileum of patients with Crohn’s disease
Li et al. 2016c Cell Immunol 304-305: 63-68

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Group 1 ILCs (ILC1) & Inflammatory Bowel Disease (IBD)

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