meRfi®-GM
Aging / Senescence
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Contents
Aging is a big risk factor for long-term illnesses, problems with organs, and a drop in the body's ability to heal itself.
12 hallmarks of aging: Genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, [chronic inflammation](brain://8C…
References (Sources)
- An update of the oxidation-inflammation theory of aging: the involvement of the immune system in oxi-inflamm-aging
- Hallmarks of Aging: An Autophagic Perspective
- Hallmarks of aging: An expanding universe
- Immunosenescence and Its Hallmarks: How to Oppose Aging Strategically? A Review of Potential Options for Therapeutic Intervention
- Immunosenescence, inflammaging, and frailty: Role of myeloid cells in age-related diseases
- Is inflammageing influenced by the microbiota in the aged gut? A systematic review
- Meta-inflammaging at the crossroad of geroscience