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Cardiac glycoside reductase 2 (Cgr2) is sufficient to induce IL-17a, a major T helper 17 cell cytokine.
Cardiac glycoside reductase 2 (Cgr2)+ E. lenta depletes putative steroidal glycosides in pure culture; related compounds are negatively associated with human Inflammatory Bowel Disease (IBD) severity.
The cgr2 gene correlates with [Inflammatory Bowel Disease (IBD)](brain://UUceGF1S-UOZoI1lctf08Q/Inflamma…