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Noncanonical Planar Cell Polarity Pathway / Planar Cell Polarity Pathway
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Contents
The Planar Cell Polarity (PCP) pathway is a highly conserved signaling mechanism that plays crucial roles in various developmental and physiological processes. This pathway is responsible for establishing and maintaining cell and tissue polarity along the plane of an epithelium, as well as regulating directional cell behaviors.
The Planar Cell Polarity Pathway pathway is considered a non-canonical Wnt signal transduction pathways, involving Wnt ligands and Frizzled family receptors but operating independently of beta-catenin-driven gene expression
The planar cell polarity (PCP) pathway regulates directed cell behaviors such as migrat…