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N1-acetylspermidine is a metabolite that has been found to play a role in various biological processes, including tumor progression, stem cell fate, and as a potential biomarker in T-lymphoblastic leukemia/lymphoma monitoring.
It is a polyamine derivative that has been associated with acidic tumor microenvironments, where it accumulates and contributes to protumor immunity by stimulating the recruitment of neutrophils, angiogenesis, and Tumor growth
In the context of stem cells, N1-acetylspermidine has been identified as a dete…