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Proton Pump Inhibitors (PPIs) may alter the relative prevalence of certain organisms in the lower esophagus while having a lesser effect on the proximal esophagus. Changes in the esophageal microbiome have been correlated with some esophageal diseases.
Proton Pump inhibitors cause alterations in the composition of both the upper and distal gut microbiota. However, the functional relevance of Proton Pump inhibitors-induced dysbiosis remains unclear. The involvemen…