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Lipid droplets (LDs)
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Contents
In eukaryotes, nutrients are stored in the form of lipids and managed by atypical organelles called lipid droplets (LDs).
The cellular content of Lipid droplets (LDs) is remarkably flexible; LDs can be promptly formed or efficiently consumed depending on the cellular status
The surface of Lipid droplets (LDs) is a crowded domain
When lipids are needed, LDs are promptly but progressively activated to meet the cellular demands
These lipid droplet accumulations can be classified as macrovesicular, large lipid droplets that displace the nucleus and organelles or microv…
References (Sources)
- AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation
- Characterization of cytoplasmic lipid droplets in each region of the small intestine of lean and diet-induced obese mice in response to dietary fat
- Defensive‐lipid droplets: Cellular organelles designed for antimicrobial immunity
- Lipid droplet contact sites in health and disease
- Lipid droplets and the host-pathogen dynamic: FATal attraction?
- Lipid droplets, bioenergetic fluxes, and metabolic flexibility
- Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense